Contents
NSAIDS and Adjuncts
|
Name
|
Dosing
|
Comment
|
|
Advil
(ibuprofen)
|
|
- non-selective inhibitors of COX-1/COX-2
- COX-1: stomach & kidneys
- COX-2: regulates inflammatory response in synovial tissue & is responsible for symptoms
- complications include peptic ulcer formation (bleeding) & ATN
|
|
Naprosyn
(naproxen)
|
|
- non-selective inhibitors of COX-1/COX-2
- COX-1: stomach & kidneys
- COX-2: regulates inflammatory response in synovial tissue & is responsible for symptoms
- complications include peptic ulcer formation (bleeding) & ATN
|
|
Indocid
(indomethacin)
|
|
- non-selective inhibitors of COX-1/COX-2
- COX-1: stomach & kidneys
- COX-2: regulates inflammatory response in synovial tissue & is responsible for symptoms
- complications include peptic ulcer formation (bleeding) & ATN
|
|
Cytotec
(misoprostol)
|
|
- prostaglandin E1 analog, and is used to prevent NSAID induced ulcers
|
|
Pennsaid
(diclofenac)
|
|
- topical diclofenac solution
- NSAID GI complications not completely avoided
|
|
Arthrotec
|
|
- diclofenac (Voltaren) + misoprostol
|
|
Celebrex
(celecoxib)
|
|
- selective COX-2 inhibitor
- no GI complications, but contraindicated in pts. with cardiac/stroke risk factors
|
Other
|
Name
|
Dosing
|
Comment
|
|
Tylenol
(acetaminophen)
|
- 325-1000 mg po/pr q6h prn
|
- analgesic & antipyretic properties
- toxic at >140 mg/kg or > 7.5 g in 24 hours
|
|
Vitamin D
(calciferol)
|
|
|
|
Calcium
|
|
|