Benign
- Chondroblastoma
- Giant cell tumor
Malignant
- Clear cell chondrosarcoma
Notes
- Chondroblastoma is typically geographic and confined to the epiphysis until late in its course; punctate calcification may be observed.
- Giant cell tumors are subarticular lesions usually extending across the epiphyseal-metaphyseal region.
- Clear cell chondrosarcoma is a rare, low-grade lesion frequently found in the epiphyseal or epiphyseal-metaphyseal region of the proximal humerus or proximal femur. It may be difficult to differentiate from chondroblastoma on radiographic features.
- Juxta-articular lesions and epiphyseal lesions overlap if the juxta-articular changes are only on one side of the joint.
Other Differential Diagnoses by Anatomic Location
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