Access Keys:
Skip to content (Access Key - 0)

Epiphyseal-metaphyseal bone lesions

Non-tumor

  • Brown's tumor of hyperparathyroidism

Benign

  • Osteoblastoma
  • Chondroblastoma
  • Aneurysmal bone cyst
  • Giant cell tumor (included as benign aggressive, although rarely metastases may occur)

Malignant

  • Telangiectatic osteosarcoma
  • Conventional osteosarcoma

Notes

  • Giant cell tumor is the most common diagnosis in this group.
  • Aneurysmal bone cyst should be suspected in patients with open growth plates and from fluid_fluid levels on MRI or CT.
  • Features of osteoblastoma, giant cell tumor, and aneurysmal bone cyst are often present on histology from the same tumor.
  • Always do serum calcium to rule out Brown's tumor.
  • If a large associated soft tissue mass is present, consider telangiectatic osteosarcoma.
  • Classic (non-telangiectatic) osteosarcoma may extend across the physis in children or across the growth plate scar in skeletally mature individuals. It is recognized by the presence of osteoid formation and the development of a soft tissue mass on top of the intact cortex.

Other Differential Diagnoses by Anatomic Location

Peer Review

OrthopaedicsOne Peer Review Workflow is an innovative platform that allows the process of peer review to occur right within an OrthopaedicsOne article in an open, transparent and flexible manner. Learn more

Instructions for Authors

Read our Instructions for Authors to learn about contributing or editing articles on OrthopaedicsOne.

Content Partner

Learn about becoming an OrthopaedicsOne Content Partner.

Academic Resources

Resources on Epiphyseal-metaphyseal bone lesions from Pubget.

The license could not be verified: License Certificate has expired!
Orthopaedic Web Links

Internet resources validated by OrthopaedicWebLinks.com

The license could not be verified: License Certificate has expired!
Related Content

Resources on Epiphyseal-metaphyseal bone lesions and related topics in OrthopaedicsOne spaces.

Page: Polyostotic conditions (OrthopaedicsOne Articles)
Page: Juxta-articular bone lesions (OrthopaedicsOne Articles)
Page: Epiphyseal bone lesions (OrthopaedicsOne Articles)
Page: Epiphyseal-metaphyseal bone lesions (OrthopaedicsOne Articles)
Page: Metaphyseal and metaphyseal-diaphyseal bone lesions (OrthopaedicsOne Articles)
Page: Diaphyseal bone lesions (OrthopaedicsOne Articles)
Page: Parosteal bone lesions (OrthopaedicsOne Articles)
Page: Anterior bone spine (OrthopaedicsOne Articles)
Page: Posterior bone spine (OrthopaedicsOne Articles)
Page: Sacrum bone lesions (OrthopaedicsOne Articles)
Showing first 10 of 231 results