Access Keys:
Skip to content (Access Key - 0)

How large is the lesion

To answer this question (and actually measure the lesion), ensure that the full lesion is critically analyzed. Evaluating the total extent of skeletal involvement may also provide clues to any systemic alterations that relate to the diagnosis.

In general, the larger the lesion, the more likely it is to be aggressive or malignant. Conversely, smaller lesions, such as an osteoid osteoma, are usually benign. This is not universally true, of course; some very extensive lesions, such as fibrous dysplasia, may be quite large and remain benign.

The assessment of the extent skeletal involvement begins with local radiographs; Xrays of other sites or a bone scan may be needed. Generalized osteoporosis evident in the initial Xray may be a feature of diffuse bony involvement with multiple myeloma. In metastatic bone disease, other lesions may be seen in the same Xray. Besides these malignant conditions, endocrine conditions, congenital diseases (familial osteochondromatosis), or developmental skeletal dysplasia (Ollier's disease, Maffucci's disease) may become obvious when the skeleton surrounding the primary lesion is examined. Systemic diseases of bone, such as Paget's disease, are often discovered by evaluating the bone peripheral to the primary lesion.

A total body bone scan is very valuable in assessing the extent of the generalized skeletal abnormality. This test will usually diagnose multiple metastases, or skeletal involvement by systemic disease (Paget's disease), as well as demonstrate the activity of bone remodelling at the local site.

The Other Questions to Ask

Peer Review

OrthopaedicsOne Peer Review Workflow is an innovative platform that allows the process of peer review to occur right within an OrthopaedicsOne article in an open, transparent and flexible manner. Learn more

Instructions for Authors

Read our Instructions for Authors to learn about contributing or editing articles on OrthopaedicsOne.

Content Partner

Learn about becoming an OrthopaedicsOne Content Partner.

Academic Resources

Resources on How large is the lesion from Pubget.

The license could not be verified: License Certificate has expired!
Orthopaedic Web Links

Internet resources validated by

The license could not be verified: License Certificate has expired!
Related Content

Resources on How large is the lesion and related topics in OrthopaedicsOne spaces.

Page: Where is the lesion (OrthopaedicsOne Articles)
Page: How large is the lesion (OrthopaedicsOne Articles)
Page: What is the lesion doing to the bone (OrthopaedicsOne Articles)
Page: What is the bone doing in response (OrthopaedicsOne Articles)
Page: What kind of matrix is being made (OrthopaedicsOne Articles)
Page: Is the cortex eroded (OrthopaedicsOne Articles)
Page: Is a soft tissue mass evident (OrthopaedicsOne Articles)
Page: Radiographic Analysis of Bone Tumors - Seven Questions to Ask (OrthopaedicsOne Articles)
Page: Polyostotic conditions (OrthopaedicsOne Articles)
Page: Juxta-articular bone lesions (OrthopaedicsOne Articles)
Showing first 10 of 227 results