Factors affecting fracture healing

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Blood Supply

  • Soft tissue injury
  • Radiation
  • Chemical or thermal burns
  • Infection
  • Anaemia and hypoxia
  • Denervation
  • Excessive compression (more than 30lbs)
  • Age

Excessive Movement

  • Inadequate immobilisation
  • Inadequate fixation or compliance

Gap

  • Interposed soft tissue
  • Distraction of bones

Other

  • Nutrition (Vit C required for normal collagen)
  • Drugs (corticosteriods inhibit osteoblast differentiation)
Etiology of Pathological Fractures  Factors affecting wound healing
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