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Page: How large is the lesion (OrthopaedicsOne Articles)
To answer this question (and actually measure the lesion), ensure that the full lesion is critically analyzed. Evaluating the total extent of skeletal involvement may also provide clues to any systemi…
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Page: Is a soft tissue mass evident (OrthopaedicsOne Articles)
MRI and CT scan are generally better at showing typical soft tissue masses than plain radiographs. However, it is often possible to visualize abnormalities in the soft tissues surrounding bone on conv…
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Page: Is the cortex eroded (OrthopaedicsOne Articles)
Cortical erosion is the hallmark of the active, aggressive or malignant tumor, and the pattern of cortical erosion may be highly correlated with the histology of the lesion: In chondrosarcoma, (unicam…
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Page: Radiographic Analysis of Bone Tumors - Seven Questions to Ask (OrthopaedicsOne Articles)
Plain radiographs are the most important investigation for bone tumors. In fact, four of the five common clinical scenarios described in the section Musculoskeletal Tumors - The Five Presenting Compla…
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Page: What is the bone doing in response (OrthopaedicsOne Articles)
The affected bone has a limited ability to  respond to the lesion, just as the tumor has a limited number of potential effects on the skeleton. Often, the bone responds by making new bone, which can b…
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Page: What is the lesion doing to the bone (OrthopaedicsOne Articles)
Bone tumors have a limited number of potential effects on the skeleton. The most common is to produce bone lysis. The pattern of lysis and the extent of the host response to lysis (which is defined in…
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Page: What kind of matrix is being made (OrthopaedicsOne Articles)
The question of what type of matrix is being made is fundamental to the diagnosis of primary mesenchymal tumors, especially benign and malignant bone and cartilage forming tumors. Besides the patterns…
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Page: Where is the lesion (OrthopaedicsOne Articles)
This is the most important question to ask when developing a differential diagnostic list: The particular bone involved as well as the portion of the bone affected must be determined. The Affected Bon…
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