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Page: Cartilage and Bone Regeneration Using Gene-Enhanced Tissue Engineering (OrthopaedicsOne Articles)
Abstract Joint cartilage injury remains a major problem in orthopaedics with more than 500,000 cartilage repair procedures performed yearly in the United States at a cost of hundreds of millions of do…
Page: Cartilage Damage by Matrix Degradation Productions - Fibronectin Fragments (OrthopaedicsOne Articles)
Abstract Catabolic cytokines play a major role in cartilage degradation not only in rheumatoid arthritis but also in osteoarthritis. Although the major source in rheumatoid arthritis may be mononuclea…
Page: Cartilage Imaging Techniques - Current Clinical Applications and State of the Art Imaging (OrthopaedicsOne Articles)
Abstract The high incidence of cartilage lesions, coupled with the recent advances for their surgical and nonsurgical treatment, have necessitated the development of techniques for accurate diagnosis …
Page: Cartilage Regeneration Using Principles of Tissue Engineering (OrthopaedicsOne Articles)
Abstract It is well known that articular cartilage in adults has a limited ability for self-repair. Numerous methods have been devised to augment its natural healing response, but these methods genera…
Page: Cartilage Tissue Engineering - Current Limitations and Solutions (OrthopaedicsOne Articles)
Abstract Articular cartilage repair remains one of the most intensely studied orthopaedic topics. To date the field of tissue engineering has ushered in new methodologies for the treatment of cartilag…
Page: Chemokines in Cartilage Degradation (OrthopaedicsOne Articles)
Abstract Besides the well-known activities of the prototypical inflammatory cytokines (IL-beta, TNF alpha), a role for chemokines and their receptors in cartilage degradation in osteoarthritis has rec…
Page: Chondral Defects in Animal Models - Effects of Selected Repair Procedures in Canines (OrthopaedicsOne Articles)
Abstract The defect made to the level of the tidemark in a canine model has been used in several prior investigations of various articular cartilage repair procedures. Direct comparison of the repair …
Page: Chondrocyte Senescence, Joint Loading and Osteoarthritis (OrthopaedicsOne Articles)
Abstract Cellular level is not completely understood, but both aging and loading-induced stresses have been shown to undermine cell functions related to the maintenance and restoration of the cartilag…
Page: Chondrogenitor Cells and Gene Therapy (OrthopaedicsOne Articles)
Abstract The development of isolation and culture techniques for mesenchymal progenitor cells from various tissues has promoted interest in the use of these cells for repair and regeneration of muscul…
Page: Chonodrogenesis in Cartilage Repair Is Induced by Members of the Transforming Growth Factor-Beta Superfamily (OrthopaedicsOne Articles)
Abstract The authors recently reported on the principle of an intrinsic repair strategy for partial-thickness articular cartilage defects, which is based on the introduction of a biocompatible and bio…