Location

Spine

Diagnosis

Sickle cell disease

Discussion

Lateral radiograph of the spine reveals central endplate depression with sparing of the anterior and posterior margins of the endplate. Several current names have been ascribed to these changes seen in patients with hemoglobinopathy, such as Lincoln Log Sign and H-shaped vertebra. Although not pathognomonic, these terms are typically reserved for a patient with sickle cell disease.

Reference

Hansen GC, Gold RH: Central depression of multiple vertebral end-plates: a “pathognomonic” sign of sickle hemoglobinopathy in Gaucher’s disease AJR Am J Roentgenol 1977 Aug;129(2):343-4.

Figures

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Attachments:


spinehvertebra.jpg (image/jpeg)