Malignant lesions may be characterized by a number of radiographic changes, including multiple lesions (metastatic lesions seen on bone scan), permeative bone destruction with poorly defined margins, cortical erosion, malignant matrix formation, and the development of a soft tissue mass.

  • In differentiating mesenchymal from metastatic bone malignancies, it is useful to determine if the tumor is solitary or multiple.
  • Matrix formation and an associated soft tissue mass are more frequent with mesenchymal lesions.

The Other Types of Biological Potential