- A rare tumor usually occurring in persons age 10-30 years
- Patients usually present with pain and swelling of variable duration
- Tumor most frequently located in distal femur and humerus, most are metaphyseal
- Lesion may be sclerotic or mixed osteolytic/osteosclerotic
- Permeative border and Codman’s triangle usually present
- Soft tissue mass present in majority of cases
- Histologically, sheets of small, round, blue cells observed
- Appearance is similar to that of Ewing sarcoma, but differs from Ewing in that these cells produce osteoid
- Use of Ewing immunohistochemical markers and evaluation for an 11:22 chromosomal translocation useful to eliminate a diagnosis of Ewing sarcoma
Last Updated on June 27, 2024
🔗 Knowledge Graph & Clinical Correlates
OrthopaedicsOne Living Semantic Network🛠️ Operative Techniques
- Total scapular resections with endoprosthetic reconstruction Musculoskeletal Tumor
🩺 Clinical Conditions & Indications
- Who should undergo biopsy of a bone lesion Patient selection for a biopsy is important: It is intended to confirm the radiologic diagnosis in patients with...
- Who should do the biopsy of a bone lesion Clinical studies undertaken by the Musculoskeletal Tumor Society have documented a high incidence of problems suffered by patients...
- Where is the lesion Original Clinical Contribution: Authored for the OrthopaedicsOne Musculoskeletal Oncology Specialty Section. Preserved, digitized, and updated to modern evidence-based...
- What is the lesion doing to the bone Bone tumors have a limited number of potential effects on the skeleton. The most common is to produce...
🔬 Anatomy, Pathology & Diagnostics
- What kind of matrix is being made Generalized Bone and Joint
- Validation of cDNA Microarray Analysis to Distinguish Tumor Type Ex Vivo Generalized Bone and Joint
- Urokinase Plasminogen Activator System – A Multifunction Role in Tumour Progression and Metastasis Pelvis and Acetabulum
- Tumor Classifications Hip Joint & Proximal Femur