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- Monostotic lesions cease activity at puberty, but may be reactivated by pregnancy
- Polyostotic presents with pathological fracture in 85%
- Rarely show malignant change (<1%), unless after radiotherapy
Albright Disease
- A varaint of Fibrous Dysplasia
- Female more than Male
- Consists of
- Polyostotic disease (unilateral usually)
- Skin pigmentation (coast of Maine)
- Endocrinopathy (Precocious puberty)
Osteofibrous Dysplasia
- Rare variant of Fibrous Dysplasia
- Seen in young children
- Usually affects tibial cortex
- Mostly asymptomatic
- May present with local tenderness or bowing of tibia
- Highly vaiable appearance on X-Ray
- Histology is similar to Fibrous Dysplasia, but has osteoblastic rimming
- No treatment necessary, unless symptomatic
