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Fibrous Dysplasia

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  • Monostotic lesions cease activity at puberty, but may be reactivated by pregnancy
  • Polyostotic presents with pathological fracture in 85%
  • Rarely show malignant change (<1%), unless after radiotherapy

Albright Disease

  • A varaint of Fibrous Dysplasia
  • Female more than Male
  • Consists of
    • Polyostotic disease (unilateral usually)
    • Skin pigmentation (coast of Maine)
    • Endocrinopathy (Precocious puberty)

Osteofibrous Dysplasia

  • Rare variant of Fibrous Dysplasia
  • Seen in young children
  • Usually affects tibial cortex
  • Mostly asymptomatic
  • May present with local tenderness or bowing of tibia
  • Highly vaiable appearance on X-Ray
  • Histology is similar to Fibrous Dysplasia, but has osteoblastic rimming
  • No treatment necessary, unless symptomatic