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- Contrast osteoarthritis with rheumatoid arthritis. ? If both rheumatoid arthritis and osteoarthritis can lead to end-stage destruction of the joint(and both can) why is it important to differentiate between the two?
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- What are the three tasks of bone: skeletal homeostasis, mineral homeostasis and hematopoesis. How ? How can problems related to these latter the two non-structural tasks lead to fracture?
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- What are the three fractures typically associated with osteoporosis? Which is worst? Why is it so bad?
- Heaney wrote, "Although bone mass is certainly the most extensively studied of the fragility factors, low bone mass is not the whole of the osteoporosis story and may not even be its most important component (despite frequent assertions to the contrary). If one could magically normalize bone mass in everyone, would one eliminate osteoporotic fractures? The best answer that can be given today is ‘no.’ There would be fewer such fractures, but there would still be many, especially hip fractures." (Heaney RP Bone Mass, Bone Loss, and Osteoporosis Prophylaxis. Annals Internal Medicine 15 February 1998 128: 313-314). Explain what Heaney meant. That is, What else besides intrinsic bone problems could cause hip fracture?
- Mr. Smith, a 72 year old with hip pain, had x-rays ordered by his PCP that showed lytic lesions concerning for bone cancer. The radiology report, however, read the films as “Paget’s Disease” to which Mr. Smith exclaimed with delight, “It’s not cancer! That’s great news! What is Pagets disease of the bone? And why might that diagnosis not be "great news"?
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- What are the necessary conditions for appropriate bone healing (leading to minimal functional residuals) and how may physicians optimize the chances for healing?
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- What is compartment syndrome and how is it prevented, diagnosed, and treated? What are the consequences of not treating a compartment syndrome and over-treating a suspected compartment syndrome?
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