Workshop held in November 1999, manuscripts published as a supplement to the October 2000 issue ofClinical Orthopaedics and Related Research®(CORR)

Issue Table of Contents

Orthopaedic Gene Therapy

Studies on the Chemical Nature of the Substance Inducing Transformation of Pneumococcal Types – Induction of Transformation by a Desoxyribonucleic Acid Fraction Isolated from Pneumococcus Type III

Genes and Gene Expression

Vector Systems for Gene Transfer to Joints

The Adeno-Associated Virus Vector for Orthopaedic Gene Therapy

Human Genetic Insights into Skeletal Development, Growth, and Homeostasis

Gene Therapy – Clinical Considerations

The Ethics of the Introduction of Gene Therapy into Orthopaedic Practice

Orthopedic Gene Therapy – Disease Targets

Mesenchymal Stem Cells and Gene Therapy

Mesenchymal Stem Cells as Vehicles for Gene Delivery

Hematopoietic Stem Cells

Orthopaedic Gene Therapy – Stem Cells for Gene Delivery

Osteoinductive Applications of Regional Gene Therapy – Ex Vivo Gene Transfer

In Vivo Nonviral Delivery Factors to Enhance Bone Repair

Potential Role of Direct Adenoviral Gene Transfer in Enhancing Fracture Repair

Potential of Gene Therapy for Treating Osteogenesis Imperfecta

Pluripotential Mesenchymal Cells Repopulate Bone Marrow and Retain Osteogenic Properties

Marrow Transplantation and Targeted Gene Therapy to the Skeleton

Orthopaedic Gene Therapy – Fracture Healing and Other Nongenetic Problems of Bone

Gene Therapy for Genetic Diseases of Bone

Chondrogenitor Cells and Gene Therapy

Cartilage and Bone Regeneration Using Gene-Enhanced Tissue Engineering

Type II Interleukin-1beta Receptor – A Candidate for Gene Therapy in Human Arthritis

Nonviral In Vivo Gene Therapy for Tissue Engineering of Articular Cartilage and Tendon Repair

Insulinlike Growth Factor-I Gene Therapy Applications for Cartilage Repair

Using Gene Therapy to Protect and Restore Cartilage

Gene Therapy for Chondrocytes

Orthopaedic Gene Therapy – Chondroprogenitors

Gene Therapy for Spine Fusion

Potential Applications of Gene Therapy to the Treatment of Intervertebral Disc Disorders

Complexity of Determining Cause and Effect In Vivo after Antisense Gene Therapy

In Vivo Gene Transfer into Tendon by Recombinant Adenovirus

Orthopaedic Gene Therapy – Spine

Orthopaedic Gene Therapy – Ligament and Tendon

Gene Therapy for Osteoarthritis – New Perspectives for the Twenty-First Century

Evaluation of Gene Therapy as a Treatment for Equine Traumatic Arthritis and Osteoarthritis

Gene Therapy Approaches for Treating Rheumatoid Arthritis

Clinical Trials in the Gene Therapy of Arthritis

Gene Therapy for Rheumatoid Arthritis

Orthopaedic Gene Therapy – Osteoarthritis