Non-tumor

  • Dural cyst

Benign

  • Giant cell tumor
  • Aneurysmal bone cyst

Malignant

  • Chordoma
  • Chondrosarcoma

Notes

  • Dural cysts cause expansion of the canal with long-standing bony remodeling.
  • Chordoma is a midline tumor with anterior and posterior expansion and frequent anterior soft tissue mass.
  • Giant cell tumor frequently extends to sacral ala, while chondrosarcoma usually demonstrates typical chondroid matrix formation.

Other Differential Diagnoses by Anatomic Location